Fluoxetine - a weak clinical indicator - Comment

Hi,

but surprisingly they "were not helped by fluoxetine,"

It may be a very interesting and fruitful discovery. However, as I see in my clinical practice - fluoxetine is rather an 'average' antidepressant and therefore, I don’t like the idea to treat it as a reference point. As it was discovered as the first SSRI, it may be a bit 'outdated' nowadays. I use it mostly often to treat patients with bulimia nervosa, but I prefer more modern SSRIs, like citalopram, or its active metabolite - escitalopram. The last one is my 'favorite' antidepressant - it's reliable, the first effects of the treatment appear faster comparing to other SSRIs and it’s generally very well tolerated by the patients. The problem is that escitalopram is much more expensive than other SSRIs. However, the patients in USA are in a more comfortable situation, as the generic drug has been approved by FDA.

BTW, welcome back after so many months, I do hope you still remember me :)

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